An underground market for unapproved weight-loss medications is propelled by TikTok fitness influencers and vendors on messaging platforms, according to new investigations.
Retatrutide, which remains in clinical trials, is being promoted by online personalities for its supposed weight-reducing effects. Followers are urged to contact these accounts directly for supplier links, while also obtaining promotional offers.
Additionally, a flourishing trade exists on messaging services, where communities with thousands of participants share comparison photos, administration instructions and assertions of next-day UK delivery. Sellers promote the substance there before directing customers to WhatsApp for transactions.
Retatrutide is an investigational injectable developed by US drugmaker Eli Lilly. The drug targets three gut hormones – GLP-1, glucose-dependent insulinotropic polypeptide and pancreatic hormone. Early trials suggest it could help individuals reduce up to a quarter of their total weight. Referred to as the “triple G”, the substance is being hailed digitally as the next Ozempic.
However, physicians and chemists have warned that the sale of what is still an unapproved medication in the United Kingdom is a cause for concern and could lead to users administering products of uncertain source.
Some experts stated the demand for the experimental drug could be linked to the rising price of approved weight loss products such as Mounjaro.
Selling the unapproved drug on social media or messaging apps is illegal in the UK, as it is an unlicensed medication that must not be promoted or supplied for human use under the Human Medicines Regulations 2012.
Several content creators try to sidestep the regulations by referring to the drug as a “research chemical” or citing it as “not for human consumption”. The substance is not a restricted drug, but promotion and supply can still breach medicines, advertising, and consumer regulations, risking penalties, prosecution or prison.
According to TikTok, the service has removed violative material and prohibited related keywords and search suggestions. The company said it was committed to maintaining the service secure and allocating resources in strengthening compliance measures.
Research also discovered communities with up to nine thousand members selling retatrutide using the platform's integrated discovery tool, which functions like a public directory. Typing “retatrutide” instantly brings up channels with thousands of users, filled with photos of slimming results, positive testimonials and step-by-step instructions for preparing or injecting at home.
Within minutes of joining one community, a vendor posted WhatsApp details, where the majority of transactions occur. The seller provided an instruction manual and guaranteed delivery within 48 hours. When asked whether the product was genuine, one seller said: “You can’t be sure.” Another shared a photo of a supposed testing documentation. Not one asked about body mass, medical conditions or past usage.
Inside these groups, messages show dark colored packages with Royal Mail labels, stating to include new batches. One message read: “It took eight of us to load them this morning.”
Buyers can choose between dry substance containers, prepared at residence with purified liquid, or ready-to-use pens usually priced at £160 for 20mg. When questioned how much time a injector should last, sellers give conflicting answers varying between a few weeks to “depends on your body”.
A spokesperson for the messaging service said it actively moderated dangerous content on its service including material that encouraged the “misuse of controlled medications”. The company added that it eliminated “millions of pieces of harmful content each day”.
“People are injecting materials they cannot confirm. Even if the science behind retatrutide is valid, these online versions may not contain what they claim,” stated a pharmacy expert, the head of pharmacy at a pharmacy service.
Dr Crystal Wyllie of an online medical service linked the increase in demand to recent price rises for authorized weight-loss drugs such as Mounjaro. “With prices rising, individuals are using online platforms. But counterfeit injections are extremely risky. You cannot know what’s contained or whether the environment they were produced in was clean,” she explained.
Her staff has already encountered individuals harmed by personal administration from unconfirmed sources. “We recognize the frustration, but purchasing from Telegram or communication platforms is gambling with your well-being,” said Wyllie. “These substances could be contaminated or incorrectly dosed.”
A spokesperson from the pharmaceutical company said the substance was in phase 3 clinical trials and had not been evaluated or authorized by any government authority anywhere in the world. “Consequently at this point no one can market [it] for personal consumption,” they explained, adding that any product “misleadingly claiming itself as a Lilly investigational product not yet approved … may expose users to potentially significant medical dangers”.
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